Endoplasmic reticulum stress and apoptosis
| Autor: | Jitka Faitova, Roman Hrstka, Borivoj Vojtesek, Daniel Krekac |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: |
p53
Programmed cell death Protein Folding Scotin Endoplasmic reticulum Apoptosis Cell Biology Disease Biology Endoplasmic Reticulum Biochemistry Molecular medicine Article Cell biology Oxidative Stress Organelle Animals Humans Molecular Biology Signalling pathways Calcium signaling Signal Transduction |
| Zdroj: | Cellular & Molecular Biology Letters |
| ISSN: | 1689-1392 1425-8153 |
| Popis: | Cell death is an essential event in normal life and development, as well as in the pathophysiological processes that lead to disease. It has become clear that each of the main cellular organelles can participate in cell death signalling pathways, and recent advances have highlighted the importance of the endoplasmic reticulum (ER) in cell death processes. In cells, the ER functions as the organelle where proteins mature, and as such, is very responsive to extracellular-intracellular changes of environment. This short overview focuses on the known pathways of programmed cell death triggering from or involving the ER. |
| Databáze: | OpenAIRE |
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