Figure S2 from Functional Ex Vivo Assay Reveals Homologous Recombination Deficiency in Breast Cancer Beyond BRCA Gene Defects

Autor:	Dik C. van Gent, Agnes Jager, John W.M. Martens, Roland Kanaar, Harmen J.G. van de Werken, Marcel Smid, Petra M. Nederlof, Esther Lips, Winand N.M. Dinjens, T. Dorine den Toom, Hendrikus-Jan Dubbink, Hein F.B.M. Sleddens, Michael A. den Bakker, Carolien H.M. van Deurzen, Kishan A.T. Naipal, Job van Riet, Anieta M. Sieuwerts, Nicole S. Verkaik, Titia G. Meijer
Rok vydání:	2023
Popis:	BRCA1 promoter hypermethylation and RNA in situ hybridization by RNAscope. M248, M253, M112 and M232 clearly showed presence of BRCA1 RNA, whereas in M94 (BRCA1 deletion) no BRCA1 RNA was present. M131 and M277 showed heterogeneous presence of BRCA1 RNA. PPIB probe = positive control
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2827c3e4bd4d34908bd75437d10a77c8 https://doi.org/10.1158/1078-0432.22467974 Zobrazit plný text záznamu