Catheter-directed thrombolysis for patients with acute lower extremity deep vein thrombosis: a meta-analysis
| Autor: | Zhang Zeju, Wang Li, Zhang Chuanlin, Chao Hsing Yeh, Chen Liqun, Mu Shaoyu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Venous Thrombosis
lcsh:RT1-120 Efficacy lcsh:Nursing Trombose Venosa profunda de la Extremidad Superior Anticoagulants Review Article 030204 cardiovascular system & hematology 030218 nuclear medicine & medical imaging 03 medical and health sciences Trombose de la Vena Treatment Outcome 0302 clinical medicine Lower Extremity Upper Extremity Deep Vein Thrombosis Eficacia Acute Disease Catheterization Peripheral Humans Thrombolytic Therapy Metaanálisis Meta-Analysis |
| Zdroj: | Revista Latino-Americana de Enfermagem, Vol 26, Iss 0 (2018) Revista Latino-Americana de Enfermagem |
| ISSN: | 1518-8345 |
| Popis: | Objectives: To evaluate case series studies that quantitatively assess the effects of catheter-directed thrombolysis (CDT) and compare the efficacy of CDT and anticoagulation in patients with acute lower extremity deep vein thrombosis (DVT). Methods: Relevant databases, including PubMed, Embase, Cochrane, Ovid MEDLINE and Scopus, were searched through January 2017. The inclusion criteria were applied to select patients with acute lower extremity DVT treated with CDT or with anticoagulation. In the case series studies, the pooled estimates of efficacy outcomes for patency rate, complete lysis, rethrombosis and post-thrombotic syndrome (PTS) were calculated across the studies. In studies comparing CDT with anticoagulation, summary odds ratios (ORs) were calculated. Results: Twenty-five articles (six comparing CDT with anticoagulation and 19 case series) including 2254 patients met the eligibility criteria. In the case series studies, the pooled results were a patency rate of 0.87 (95% CI: 0.85-0.89), complete lysis 0.58 (95% CI: 0.40-0.75), rethrombosis 0.11 (95% CI: 0.06-0.17) and PTS 0.10 (95% CI: 0.08-0.12). Six studies comparing the efficacy outcomes of CDT and anticoagulation showed that CDT was associated with a reduction of PTS (OR 0.38, 95%CI 0.26-0.55, p |
| Databáze: | OpenAIRE |
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