| Autor: |
Luciana Patrícia Lima Alves Pereira, Edilene Carvalho Gomes Ribeiro, Maria Cristiane Aranha Brito, Fernanda Oliveira Sousa Araruna, Felipe Bastos Araruna, José Antonio Costa Leite, Daniella Patrícia Brandão Silveira, Taiane Maria de Oliveira, Selma Patrícia Diniz Cantanhede, Wellyson da Cunha Araújo Firmo, Odair dos Santos Monteiro, José Guilherme Soares Maia, Klinger Antonio da Franca Rodrigues, Denise Fernandes Coutinho |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Acta Tropica. 230:106393 |
| ISSN: |
0001-706X |
| DOI: |
10.1016/j.actatropica.2022.106393 |
| Popis: |
Schistosomiasis is one of the most important tropical diseases. A fundamental strategy to control its spread is the use of natural products against its vectors, which are snails of the genus Biomphalaria. The present study evaluated the chemical composition, the molluscicidal and cercaricidal effects, and the ecotoxicity of the essential oil from the aerial parts of Dysphania ambrosioides (L.) MosyakinClemants (DAEO). The essential oil was obtained by hydrodistillation and analyzed by gas chromatography-mass spectrometry (GC-MS). Molluscicidal and cercaricidal activities were determined by the immersion method. Environmental toxicity was assessed from bioassays using Artemia salina larvae and Danio rerio fish. DAEO presented a 0.8% yield. The GC-MS analysis revealed the predominance of hydrocarbon monoterpenes in the oil. A total of 32 constituents was identified, with α-terpinene (50.69%) being the major compound, followed by p-cymene (13.27%) and ascaridole (10.26%). DAEO was active against adult Biomphalaria glabrata snails and demonstrated lethal effect against Schistosoma mansoni cercariae, with LC |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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Full Text from ScienceDirect