Clinical evaluation of bempedoic acid for the treatment of hyperlipidaemia
| Autor: | Averna, Maurizio, Bilato, Claudio, Sesti, Giorgio, on behalf of the Italian Clinical Network on Bempedoic Acid, Andreini, Daniele, Bonora, Enzo, Campo, Gianluca, Catalini, Roberto, Ciccone, Matteo Marco, De Rosa, Salvatore, Di Mario, Carlo, Ferri, Claudio, Ferri, Nicola, Grigore, Liliana, Lanzilli, Antonio, Mandraffino, Giuseppe, Montalcini, Tiziana, Nardi, Federico, Pirro, Matteo, Pontremoli, Roberto, Prati, Francesco, Purrello, Francesco, Russo, Vincenzo, Sampietro, Tiziana, Sarzani, Riccardo, Scherillo, Marino, Scicali, Roberto, Suppressa, Patrizia, Temporelli, Pierluigi, Terrosu, Pierfrancesco, Tespili, Maurizio, Trevisan, Roberto |
|---|---|
| Přispěvatelé: | Averna M., Bilato C., Sesti G. |
| Rok vydání: | 2021 |
| Předmět: |
ATP citrate lyase
Endocrinology Diabetes and Metabolism Medicine (miscellaneous) Hyperlipidemias Pharmacology Lipid-lowering therapy Lipid-lowering treatment Medicine LDL-cholesterol Humans Dicarboxylic Acids Hypolipidemic Agents Ldl cholesterol Nutrition and Dietetics Lipid management business.industry Novel LDL-C treatment Fatty Acids Cholesterol LDL Bempedoic acid bempedoic acid lipid-lowering treatment novel LDL-C treatment Lipid lowering Cardiology and Cardiovascular Medicine business Clinical evaluation |
| Zdroj: | Nutrition, metabolism, and cardiovascular diseases : NMCD. 32(1) |
| ISSN: | 1590-3729 |
| Popis: | Bempedoic acid (BA) is a novel first-in-class oral lipid-lowering therapy. BA has been approved by the European Medicinal Agency and Food and Drug Administration and has been commercialised throughout Europe since the end of 2020 as an add-on therapy in patients at high/very-high cardiovascular risk that are not at LDL-C goals with current lipid-lowering treatments. Recently, Italian lipid management experts gathered to discuss several open questions on BA characteristics and BArelated practical clinical issues. The panel permitted collection of its opinions in a ten Q&A format. Aim: The aim of this viewpoint is to discuss and answer several open questions on BA characteristics and BA-related practical clinical issues. Data synthesis: The data includes main phase III studies, subanalysis and meta-analysis on BA. Conclusions: The panel permitted collection of its opinions in a ten Q&A format. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect