Social Learning of Acquiring Novel Feeding Habit in Mandarin Fish (Siniperca chuatsi)
| Autor: | Yaqi Dou, Jian Peng, Shan He, Xu-Fang Liang, Lin-Jie Shi, Hui Liang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0106 biological sciences
0301 basic medicine Fish Proteins appetite control gene feeding habit Foraging Zoology Biology 010603 evolutionary biology 01 natural sciences Catalysis Article Inorganic Chemistry lcsh:Chemistry 03 medical and health sciences Eating Food Preferences domestication Ca2+/calmodulin-dependent protein kinase Siniperca chuatsi Animals Physical and Theoretical Chemistry Phosphorylation Protein kinase A Molecular Biology Gene lcsh:QH301-705.5 Spectroscopy c-Fos Behavior Animal Sequence Analysis RNA Gene Expression Profiling Organic Chemistry Fishes General Medicine biology.organism_classification Social learning Computer Science Applications social learning 030104 developmental biology Gene Expression Regulation lcsh:Biology (General) lcsh:QD1-999 Predatory Behavior Forage fish mandarin fish Signal transduction |
| Zdroj: | International Journal of Molecular Sciences Volume 20 Issue 18 International Journal of Molecular Sciences, Vol 20, Iss 18, p 4399 (2019) |
| ISSN: | 1422-0067 |
| DOI: | 10.3390/ijms20184399 |
| Popis: | Social learning plays important roles in gaining new foraging skills and food preferences. However, the potential role and molecular mechanism of social learning in acquiring new feeding habits is less clear in fish. In the present study, we examined the success rate of feeding habit domestication from live prey fish to dead prey fish, as well as the food intake of dead prey fish in mandarin fish with or without feeders of dead prey fish as demonstrators. Here, we found that mandarin fish can learn from each other how to solve novel foraging tasks, feeding on dead prey fish. In addition, the analysis of gene expressions and signaling pathways of learning through Western blotting and transcriptome sequencing shows that the expression of the c-fos, fra2, zif268, c/ebpd and sytIV genes were significantly increased, and the anorexigenic pomc and leptin a expressions were decreased in fish of the learning group. The phosphorylation levels of protein kinase A (PKA) and Ca2+/calmodulin-dependent protein kinase II (CaMKII) in the learning group were significantly higher than those of the control group, while the phosphorylation level of S6 ribosomal protein (S6) was lower. With the inhibitors of PKA and CaMKII signaling and the chromatin immunoprecipitation (ChIP) assay, we further found that the social learning of new feeding habits in mandarin fish could be attributed to the activation of the CaMKII signaling pathway and then the stimulation of the expression of the c-fos gene, which might be an important transcriptional factor to inhibit the expression of the anorexigenic gene pomc, resulting in the food intake of dead prey fish in mandarin fish. Altogether, our results support the hypothesis that social learning could facilitate the acquisition of novel feeding habits in fish, and it considerably increases the rate of subsequent individual food intake and domestication through the interaction between the learning gene c-fos and the appetite control gene pomc. |
| Databáze: | OpenAIRE |
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