Hemolytic Uremic Syndrome in Dogs
| Autor: | Steven Holloway, David E. Senior, Lois Roth, C. Craig Tisher |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Male
medicine.medical_specialty Dopamine Kidney Gastroenterology Fibrin Blood Urea Nitrogen chemistry.chemical_compound Dogs Furosemide Internal medicine medicine Animals Aspartate Aminotransferases Dog Diseases Infusions Intravenous Blood urea nitrogen Creatinine General Veterinary biology business.industry Hemorrhagic gastroenteritis Alanine Transaminase Microangiopathic hemolytic anemia Acute Kidney Injury Alkaline Phosphatase medicine.disease Thrombosis Schistocyte Surgery Intestines Liver chemistry Hemolytic-Uremic Syndrome biology.protein Fluid Therapy Female business Peritoneal Dialysis medicine.drug |
| Zdroj: | Journal of Veterinary Internal Medicine. 7:220-227 |
| ISSN: | 1939-1676 0891-6640 |
| DOI: | 10.1111/j.1939-1676.1993.tb01011.x |
| Popis: | A disease syndrome similar to the hemolytic uremic syndrome of people is described in three dogs with acute renal failure. In each dog, hemorrhagic gastroenteritis preceded the onset of anuric acute renal failure. Evidence of microangiopathic hemolytic anemia (schizocytes, thrombocytopenia, and increased concentrations of fibrin split products) was present in the three dogs. Serum chemistry results showed increased concentrations of blood urea nitrogen, creatinine, and phosphorus. Ultrasound examination performed in one dog revealed increased echogenicity of the renal cortices. Treatment for anuric acute renal failure using a continuous dopamine and furosemide infusion established urine production in one of three dogs. Microscopic examination of tissue from the two dogs that underwent necropsy showed occlusion of the renal vasculature by fibrin thrombi consistent with microangiopathic arteriolar thrombosis. The pathophysiology and current knowledge of human hemolytic uremic syndrome is compared with hemolytic uremic syndrome in these dogs. |
| Databáze: | OpenAIRE |
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