Distinctive pattern of left–right asymmetry of ovarian benign teratomas in Chinese population: a 12-year-long cross-sectional study
| Autor: | Chenfeng Zhu, Jian Zhang, Xiaoqing He, Guiling Liang, Zhen Huang, Xiaofeng Wang, Hang Qi, Xiaoya Zhao |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
medicine.medical_specialty endocrine system China endocrine system diseases Adolescent Ovarian Torsion Cross-sectional study Ovarian teratoma Single Center 03 medical and health sciences Benign teratoma Young Adult 0302 clinical medicine Asian People Recurrence Medicine Humans Ovarian Teratoma Child Dominance (genetics) Aged Gynecology Aged 80 and over Ovarian Neoplasms Chinese population 030219 obstetrics & reproductive medicine business.industry Ovarian torsion Teratoma Obstetrics and Gynecology Left–right asymmetry General Medicine Middle Aged medicine.disease female genital diseases and pregnancy complications Cross-Sectional Studies 030220 oncology & carcinogenesis Female General Gynecology business International peace |
| Zdroj: | Archives of Gynecology and Obstetrics |
| ISSN: | 1432-0711 0932-0067 |
| Popis: | Purpose Given the lack of research on the left–right asymmetry of ovarian teratoma among Chinese patients, this study aimed to determine the lateral distribution and related clinical characteristics of Chinese ovarian teratoma patients treated at a single center. Methods We conducted a cross-sectional study of surgical patients pathologically diagnosed with ovarian teratomas in the gynecology inpatient department of the International Peace Maternity and Child Health Hospital in Shanghai between July 2006 and July 2018. Results Of the 4417 patients with ovarian teratoma, 3835 were finally analyzed. There were 2030 (53.24%) cases of right-sided benign ovarian teratoma versus 1783 (46.76%) cases of left-sided benign teratoma (P P = 0.033). Compared with the right-sided ovarian teratoma patients, left-sided ones had significantly high recurrence risk (OR 1.430; 95% CI 1.03–1.99). The rate of ovarian torsion in patients with ovarian mature cystic teratomas (MCTs) during intrauterine pregnancy was 3.17 versus 1.72% in non-pregnant MCT patients (P = 0.049). For those MCT patients with intrauterine pregnancy, ovarian torsion occurs more often on the right side (left vs. right = 16.67 vs. 83.33%, P = 0.028). Conclusion This study confirms a distinctive right-side dominance of benign ovarian teratomas. Compared with the right side, recurrent ovarian teratomas occur more often on the left side, requiring close follow-up. Intrauterine pregnancy may increase the risk of ovarian torsion, particularly on the right side, in MCT patients. |
| Databáze: | OpenAIRE |
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