Suspected chronic pancreatitis with normal MRCP: Findings on MRI in correlation with secretin MRCP
| Autor: | Frank R. Burton, Louis Magas, N. Cem Balci, Amir Javad Momtahen, Samer Alkaade |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
Gadolinium DTPA Male medicine.medical_specialty Adolescent Cholangiopancreatography Magnetic Resonance Contrast Media Gastroenterology Secretin Diagnosis Differential Pancreatitis Chronic Ectasia Internal medicine Image Interpretation Computer-Assisted medicine Humans Radiology Nuclear Medicine and imaging Pancreatitis chronic Aged Retrospective Studies Pancreatic duct Chi-Square Distribution medicine.diagnostic_test business.industry Magnetic resonance imaging Middle Aged medicine.disease medicine.anatomical_structure Pancreatitis Female Pancreas business Chi-squared distribution |
| Zdroj: | Journal of Magnetic Resonance Imaging. 27:125-131 |
| ISSN: | 1522-2586 1053-1807 |
| DOI: | 10.1002/jmri.21241 |
| Popis: | Purpose To review pancreatic MRI findings and their relationship with estimated pancreatic exocrine function on secretin-stimulated MR cholangiopancreatography (S-MRCP) in patients with clinically suspected chronic pancreatitis and normal baseline MRCP findings. Materials and Methods MRI findings of 26 patients with normal pancreatic duct diameter and without side branch ectasia on MRCP were evaluated. A single radiologist assessed pancreatic size, pancreatic signal intensity ratio (SIR), and arterial enhancement ratio (A/V) at head, body, and tail of the pancreas on T1-weighted fat-suppressed and serial contrast-enhanced images at a single session. Combined findings were graded with a composite score. Serial S-MRCP was performed at the same session with standard MRI. Correlation and differences between MRI findings and associated grade of duodenal filling (DF) or the degree of pancreatic duct caliber change (PDC) were analyzed. Results Seven patients revealed normal and 19 patients abnormal MRI findings. Significant correlation was present between the degree of DF and mean values of pancreatic size (r = 0.748), SIR (r = 0.610), A/V (r = 0.466), composite score (r = 0.833), and PDC (r = 0.554) separately. PDC correlated with SIR (r = 0.413) and composite score (r = 0.452), but not with A/V or pancreatic size. Significant differences were present between normal and abnormal DF grades in terms of mean values of associated findings of size (P = 0.001), SIR (P = 0.008), A/V (P = 0.019), and PDC (P = 0.001). Conclusion Patients with clinically suspected chronic pancreatitis and normal MRCP findings may have a spectrum of MRI findings that correlate with the estimated pancreatic exocrine insufficiency on S-MRCP with the increasing number of combined findings. J. Magn. Reson. Imaging 2007. © 2007 Wiley-Liss, Inc. |
| Databáze: | OpenAIRE |
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