A reflection-based localized surface plasmon resonance fiber-optic probe for biochemical sensing
| Autor: | Robert G. Lindquist, Yongbin Lin, Yang Zou |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Streptavidin
Optical fiber Materials science Physics::Optics Nanotechnology 02 engineering and technology 01 natural sciences law.invention 010309 optics chemistry.chemical_compound law 0103 physical sciences Surface plasmon resonance ocis:(280.1415) Biological sensing and sensors ocis:(060.2370) Fiber optics sensors Scattering business.industry ocis:(220.4241) Nanostructure fabrication Surface-enhanced Raman spectroscopy 021001 nanoscience & nanotechnology Atomic and Molecular Physics and Optics chemistry Fiber optic sensor Optoelectronics Nanodot 0210 nano-technology business Refractive index Biosensors and Molecular Diagnostics Biotechnology |
| Zdroj: | Biomedical Optics Express |
| ISSN: | 2156-7085 |
| Popis: | We report the fabrication and characterization of an optical fiber biochemical sensing probe based on localized surface plasmon resonance (LSPR) and spectra reflection. Ordered array of gold nanodots was fabricated on the optical fiber end facet using electron-beam lithography (EBL). We experimentally demonstrated for the first time the blue shift of the LSPR scattering spectrum with respected to the LSPR extinction spectrum, which had been predicted theoretically. High sensitivity [195.72 nm/refractive index unit (RIU)] of this sensor for detecting changes in the bulk refractive indices has been demonstrated. The label-free affinity bio-molecules sensing capability has also been demonstrated using biotin and streptavidin as the receptor and the analyte. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|