Enantioselective synthesis and stereoselective ring opening of N-acylaziridines

Autor:	Allen Martin, Jeremy B. Morgan, Christopher Wilhelmsen, Heather N. Rubin, Jennifer Cockrell
Rok vydání:	2012
Předmět:	Stereochemistry Aziridines Enantioselective synthesis Stereoisomerism General Medicine General Chemistry Naphthols Aziridine Ring (chemistry) Catalysis Kinetic resolution chemistry.chemical_compound Kinetics chemistry Nucleophile Stereoselectivity Enantiomer Boron
Zdroj:	Angewandte Chemie (International ed. in English). 51(39)
ISSN:	1521-3773
Popis:	Kinetic resolution of N-acylaziridines by nucleophilic ring opening was achieved with (R)-BINOL as the chiral modifier under boron-catalyzed conditions (see scheme; Ar=3,5-dinitrophenyl). The consumed enantiomer of aziridine can be further converted to an enantioenriched 1,2-chloroamide with recovery of (R)-BINOL.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e51608138ebfcaabc311461fddc165 https://pubmed.ncbi.nlm.nih.gov/22945340 Zobrazit plný text záznamu Plný text