Evaluating daily profile of central aortic pressure and reflected pulse wave parameters in climacteric women

Autor: Anton R. Kiselev, sErGEy n. Tolstov, Igor A. Salov, Andrey P. Rebrov
Rok vydání: 2021
Předmět:
medicine.medical_specialty
Time Factors
Brachial Artery
Hemodynamics
Pulse Wave Analysis
030204 cardiovascular system & hematology
Risk Assessment
03 medical and health sciences
Vascular Stiffness
0302 clinical medicine
Predictive Value of Tests
medicine.artery
Internal medicine
Diseases of the circulatory (Cardiovascular) system
Humans
Pulse pressure amplification
Medicine
Arterial Pressure
030212 general & internal medicine
Brachial artery
Aortic Pulse Pressure
Antihypertensive Agents
Aorta
business.industry
Research
Augmentation index
Blood Pressure Monitoring
Ambulatory
Middle Aged
Aortic Augmentation Index
medicine.disease
Arterial stiffness
Perimenopause
Postmenopause
Blood pressure
Heart Disease Risk Factors
RC666-701
Central aortic pressure
Hypertension
Cardiology
Aortic pressure
Female
Menopause
Cardiology and Cardiovascular Medicine
business
Zdroj: BMC Cardiovascular Disorders
BMC Cardiovascular Disorders, Vol 21, Iss 1, Pp 1-9 (2021)
ISSN: 1471-2261
DOI: 10.1186/s12872-021-02064-9
Popis: Introduction Structural and functional changes of the vascular wall in women occur already at the very early stages of reproductive aging. An emergence of applanation tonometry made it possible to evaluate arterial stiffness and central hemodynamic parameters non-invasively, which considerably expanded the information that had been provided previously by invasive methods used for studying these parameters during cardiac catheterization. Whereas a few studies have assessed central aortic pressure (CAP) parameters and reflected pulse wave in women at different phases of their reproductive aging, none investigated the daily profile of CAP and reflected pulse wave parameters in women undergoing different stages of the menopause. Background: assessment of the daily variability in CAP and daily profile of amplification and augmentation of pulse blood pressure (PBP) in women at different menopause phases. Methods The study involved 384 climacteric women. The first group included 168 women undergoing perimenopause, the second group comprised of 216 women in their early postmenopausal stage. A 24-h blood pressure (BP) monitoring in the brachial artery and aorta (BPLab® Vasotens® system, Petr Telegin LLC, Russia) was performed via the measurements of the following indicators: systolic blood pressure (SBP), pulse blood pressure (PBP), central aortic systolic pressure (CASP), central aortic pulse pressure (CAPP), aortic augmentation index (AIxao), and pulse pressure amplification (PPA). Results When investigating PPA values in the brachial artery and aorta, we detected smaller amplification and higher aortic augmentation index at night than in daytime, which reflected a disproportionately higher CAP level during night hours. This pattern was more pronounced in postmenopausal women. We calculated the logistic regression equation (adjusted R2 = 0.49, log-likelihood = − 50.3, chi-square (19) = 97.6, p Conclusion Rising CAP, in combination with declining PPA and augmenting reflected pulse wave amplitude, may be associated with an increased risk of cardiovascular complications.
Databáze: OpenAIRE
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