A review of current controversies in determining death by neurologic criteria in children
Autor: | Alexis A. Topjian, Matthew P. Kirschen, Rebecca Ichord, Akash Virupakshaiah |
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Rok vydání: | 2020 |
Předmět: |
medicine.medical_specialty
Brain Death business.industry Apnea testing Declaration MEDLINE Diagnostic Techniques Neurological Intensive Care Units Pediatric Entire brain 03 medical and health sciences 0302 clinical medicine 030225 pediatrics 030220 oncology & carcinogenesis Intensive care Pediatrics Perinatology and Child Health medicine Public trust Apnea test Humans Intensive care medicine business Child |
Zdroj: | Current opinion in pediatrics. 32(6) |
ISSN: | 1531-698X |
Popis: | Purpose of review Death by neurologic criteria (DNC) is the irreversible cessation of all functions of the entire brain, including the brainstem. It is legally recognized as equivalent to cardiopulmonary death. Legal and ethical controversies surrounding DNC have emerged as a result of several highly publicized cases that have eroded public trust in our ability to declare DNC accurately. In this review, we focus on recently published primary data about DNC and address some of these controversies. Recent findings Approximately 21% of children who die in pediatric intensive care units (PICU) are declared DNC. Although 60% of physicians report that they have been asked to maintain organ support after DNC declaration, less than 1% of patients remain physically present in the PICU more than 5 days after DNC declaration. We discuss strategies for safely conducting the apnea test, indications and prevalence of ancillary testing, and objections to DNC, including issues of consent and requests for ongoing organ support. Summary In order to maintain public trust, published guidelines must be followed to accurately and consistently diagnose DNC. We must develop strategies to respond to objections to DNC determination. Ongoing research is needed to improve the safety of apnea testing and indications for and interpretation of ancillary testing. |
Databáze: | OpenAIRE |
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