SUPLEMENTACIÓN CON AMINOÁCIDOS DE CADENA RAMIFICADA EN LA PROGRESIÓN DE LA HEPATITIS CRÓNICA
Autor: | Melina Flórez Cuadros, William Narváez Solarte, Jorge Mario Cruz Amaya |
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Jazyk: | Spanish; Castilian |
Rok vydání: | 2016 |
Předmět: |
medicine.medical_specialty
Medicine (General) QH301-705.5 Agriculture (General) Geography Planning and Development Serum albumin Leucina Management Monitoring Policy and Law Chronic liver disease Gastroenterology Enfermedad hepática S1-972 chemistry.chemical_compound aminoácidos de cadena ramificada R5-920 Fibrosis Valine Internal medicine medicine Enfermedades hepáticas Biology (General) lcsh:Agriculture (General) Aminoácidos lcsh:QH301-705.5 Chronic hepatitis branched chain amino acids lcsh:R5-920 biology business.industry Valina Aminoácidos de cadena ramificada protein malnutrition medicine.disease desnutrición proteica lcsh:S1-972 Desnutrición proteica chemistry lcsh:Biology (General) Carbon tetrachloride biology.protein Leucine medicine.symptom Isoleucine business lcsh:Medicine (General) Weight gain |
Zdroj: | Revista U.D.C.A Actualidad & Divulgación Científica, Vol 19, Iss 1, Pp 155-160 (2016) Revista U.D.C.A Actualidad & Divulgación Científica, Vol 19, Iss 1 (2016) Repositorio Institucional UDCA Universidad de Ciencias Aplicadas y Ambientales U.D.C.A instacron:Universidad de Ciencias Aplicadas y Ambientales U.D.C.A |
ISSN: | 0123-4226 |
Popis: | Malnourishment is a common condition of hepatic failure. Our objective was to evaluate the effect of supplementation with branched-chain amino acid (BCAA) in the diet of rats with chronic hepatitis. Liver damage was generated using carbon tetrachloride (CCl4) for ten weeks in all treatments except control. Experimental units were randomly assigned to six treatments: valine, leucine, isoleucine, three BCAA, CCl4and control, five replicates per treatment, and three animals per experimental unit. Serum albumin concentrations were compare. Tissue injury level was histopathologically graded from zero to three looking for disturbances such as cellular infiltration, fibrosis, and vacuolization. Also, weight gain, food intake, and liver damage signs were monitored. Samples were taken at week 6, 8, and 10. When the effect of treatment was significant (p |
Databáze: | OpenAIRE |
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