| Autor: |
Olli, Punkka, Henri-Jussi, Kurvinen, Kimmo, Koivula, Markku J, Eskola, Mika, Martiskainen, Heini, Huhtala, Vesa K, Virtanen, Jussi, Mikkelsson, Kati, Järvelä, Jari, Laurikka, Kari O, Niemelä, Pekka J, Karhunen, Andrés Ricardo, Pérez-Riera, Kjell C, Nikus |
| Přispěvatelé: |
Tampere University, TAYS Heart Centre, Clinical Medicine, Department of Clinical Chemistry, Health Sciences, BioMediTech |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Journal of Electrocardiology. 73:22-28 |
| ISSN: |
0022-0736 |
| Popis: |
Introduction: There are several potential causes of QRS-axis deviation in the ECG, but there is limited data on the prognostic significance of QRS-axis deviation in ACS patients. Subjects and methods: We evaluated the long-term prognostic significance of acute phase frontal plane QRS-axis deviation and its shift during hospital stay in ACS patients. A total of 1026 patients who met the inclusion criteria were divided into three categories: normal (n = 823), left (n = 166) and right/extreme axis (n = 37). Results: The median survival time was 9.0 years (95% CI 7.9—10.0) in the normal, 3.6 years (95% CI 2.4—4.7) in the left and 1.3 years (95% CI 0.2—2.4) in the right/extreme axis category. Both short and long-term all-cause mortality was lowest in the normal axis category and highest in the right/extreme axis category. Compared to normal axis, both admission phase QRS-axis deviation groups were independently associated with a higher risk of all-cause mortality. When including left ventricular hypertrophy in the ECG, only the right/extreme axis retained its statistical significance (aHR 1.76; 95% CI 1.16—2.66, p = 0.007). Axis shift to another axis category had no effect on mortality. Conclusion: In ACS patients, acute phase QRS-axis deviation was associated with higher risk of all-cause mortality. Among the axis deviation groups, right/extreme QRS-axis deviation was the strongest predictor of mortality in the multivariable analysis. Further studies are required to investigate to what extent this association is caused by pre-existing or by ACS-induced axis deviations. QRS-axis shift during hospital stay had no effect on all-cause mortality. publishedVersion |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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