Sporadic aniridia and Wilms' tumor: visual function evaluation of three cases
| Autor: | Véronique Jotterand, Hélène Boisjoly, Carmen Harnois |
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| Rok vydání: | 1989 |
| Předmět: |
Male
Pathology medicine.medical_specialty genetic structures Photophobia Contact Lenses Iris Nystagmus Wilms Tumor Nystagmus Pathologic Cellular and Molecular Neuroscience Intellectual Disability medicine Electroretinography Humans Vision Ocular medicine.diagnostic_test business.industry Chromosomes Human Pair 11 Vision Tests Infant Wilms' tumor medicine.disease eye diseases Sensory Systems Hypoplasia Kidney Neoplasms Contact lens Ophthalmology Aniridia Optic nerve Evoked Potentials Visual Female sense organs medicine.symptom Chromosome Deletion business |
| Zdroj: | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. 227(3) |
| ISSN: | 0721-832X |
| Popis: | The visual function of three infants with sporadic aniridia associated with Wilms' tumor and a deletion of the short arm of chromosome 11 was evaluated with electrophysiological tests. The patients presented nystagmus and photophobia. The electroretinograms (ERGs) were normal, as in other sporadic cases, but at variance with the familial cases. The latency of the flash visual evoked potentials (FVEPs) became shorter with time but remained longer than in age-matched controls, suggesting a delay in maturation of the nervous system. Poor visual function in our cases did not appear to be the result of gross retinal anomalies, as shown by the normal ERG, nor of an hypoplasia of the optic nerve. Contact lenses that provide an artificial pupil decreased photophobia and nystagmus and are therefore highly recommended to increase patient comfort. |
| Databáze: | OpenAIRE |
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