Quality of life in adolescents with heavy menstrual bleeding: Validation of the Adolescent Menstrual Bleeding Questionnaire (aMBQ)
| Autor: | Nancy L. Young, Amanda Bouchard, Kristen A. Matteson, Nancy Van Eyk, Meghan Pike, Victoria E. Price, Ashley Chopek, Koyo Usuba, Robyn McLaughlin, Mark Belletrutti |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Pediatrics
medicine.medical_specialty Receiver operating characteristic business.industry Area under the curve Mean age Hematology Original Articles heavy menstrual bleeding Menstrual bleeding Quality of life menorrhagia adolescent surveys and questionnaires Medicine Diseases of the blood and blood-forming organs Original Article RC633-647.5 patient‐reported outcome measures business skin and connective tissue diseases human activities |
| Zdroj: | Research and Practice in Thrombosis and Haemostasis Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 7, Pp n/a-n/a (2021) |
| ISSN: | 2475-0379 |
| Popis: | Background/Objectives Heavy menstrual bleeding (HMB) affects 34% to 37% of adolescent girls. The Menstrual Bleeding Questionnaire (MBQ) is a validated measure of menstrual bleeding–specific health‐related quality of life (HRQoL) for women aged ≥18 years. No similar measure existed for adolescents with HMB. Patients/Methods HMB was defined by the Pictorial Bleeding Assessment Chart (PBAC) score ≥100. In Phase 1, a focus group of adolescents with HMB adapted the MBQ, to generate the Adolescent MBQ (aMBQ). In phase 2, participants with and without HMB were recruited from clinics and self‐referral. Each participant completed 3 questionnaires (aMBQ, Pediatric Quality of Life module [PedsQL]©, PBAC) at two time points. Validity of the aMBQ was assessed by Pearson’s correlation with the PedsQL©. Reliability was calculated using intra‐class correlation (ICC) in those without HMB. The receiver operating characteristic curve assessed the aMBQ’s ability to identify those with HMB. Results Phase 1 included five girls with a mean age of 17.1 (13‐18) years. The aMBQ was adapted from the MBQ by substituting four words/phrases that altered 8 of the 20 questions and by adding 1 new question. The 21‐item aMBQ has a score range of 0 to 77 (77 = worst HRQoL). Phase 2 included 52 participants: 20 with and 32 without HMB, with a mean age of 14.8 (11‐17) years. The validity of the aMBQ was confirmed by a moderate correlation with PedsQL© (r = −0.63; P 30 identified those with HMB with excellent discrimination (area under the curve = 0.82; sensitivity, 70.0%; specificity, 84.4%). Conclusions The aMBQ is a valid and reliable tool to assess HRQoL in adolescents with HMB. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text