A revised method for the synthesis of 1,1-Bis(4-hydroxyphenyl)-2-phenylethylene (BHPE) and its derivatives

Autor:	Babak Shafii, Robert W. Atcher, Eugene R. DeSombre
Rok vydání:	1993
Předmět:	Reaction conditions Cancer Research Magnetic Resonance Spectroscopy Chemistry Group (periodic table) Stilbenes Methods Molecular Medicine Organic chemistry Radiology Nuclear Medicine and imaging Improved method Chemical synthesis
Zdroj:	Nuclear Medicine and Biology. 20:371-374
ISSN:	0969-8051
DOI:	10.1016/0969-8051(93)90062-y
Popis:	The synthesis of 1,1-bis(4-hydroxyphenyl)-2-phenylethylene, which is of biological interest, has been reported by several authors in the past. In this article an improved method is introduced. Also a protective group which is easily attached and removed is used. This procedure provides milder reaction conditions and better yields while the number of steps involved in the synthesis are reduced. Furthermore the reactions are clean and formation of by-products which lead to poorer yields are avoided.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c2384af6954b0159e68b9ce684e66e https://doi.org/10.1016/0969-8051(93)90062-y Zobrazit plný text záznamu