The role of potassium channels in the mechanism of vasodilatation of human umbilical vein induced by resveratrol
| Autor: | Helmut Heinle, Radmila Novakovic, Dragana Protić, Vladimir Kanjuh, Nebojsa Radunovic, Svetlana Spremović-Radjenović, Ljiljana Gojkovic-Bukarica |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Pharmacology
Endothelium Mechanism (biology) business.industry viruses virus diseases Vasodilation respiratory system Resveratrol Bioinformatics Umbilical vein Potassium channel 3. Good health chemistry.chemical_compound medicine.anatomical_structure Mechanism of action chemistry Meeting Abstract medicine Pharmacology (medical) medicine.symptom business K channels |
| Zdroj: | BMC Pharmacology & Toxicology |
| ISSN: | 2050-6511 |
| Popis: | Background Resveratrol (RSV) is polyphenol present in various kinds of food which we consume on daily basis. In the last ten years there has been growing importance of RSV in the literature. It is well known that RSV has many different beneficial effects on human health. RSV is partly responsible for the cardiovascular benefits of red wine. However, the mechanism of vasodilatation induced by RSV is unclear. There are many target molecules of RSV which could play an important role in the mechanism of action of RSV. The aim of our study was to define the role of K channels in the RSV-induced vasodilatation of human umbilical vein (HUV) denuded of endothelium. |
| Databáze: | OpenAIRE |
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