APA scoring system: a novel predictive model based on risk factors of pregnancy loss for recurrent spontaneous abortion patients

Autor: Yi-Fang Dai, Li-Zhen Lin, Na Lin, De-Qin He, Dan-Hua Guo, Hui-Li Xue, Ying Li, Xi Xie, Liang-Pu Xu, Shu-Qiong He
Rok vydání: 2022
Předmět:
Zdroj: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology. 42(6)
ISSN: 1364-6893
Popis: The aim of this study was to analyse the risk factors of pregnancy loss of patients with recurrent spontaneous abortion (RSA) and develop a scoring system to predict RSA. Clinical data of 242 cases, with RSA who were treated at Fujian Provincial Maternity and Children's Hospital, were selected. The factors of pregnancy loss for RSA patients were evaluated by univariate and multivariate analyses. There were 242 RSA patients, of whom 34 (14.0%) developed pregnancy loss. A multivariate analysis showed the following adverse risk factors for RSA: antinuclear antibody spectrum, protein s deficiency and antiphospholipid antibodies. The pregnancy loss rates of antinuclear antibody spectrum group, protein S deficiency group and antiphospholipid antibodies group were 25.0%, 22.5% and 19.4%, respectively. Each of these factors contributed 1 point to the risk score. The pregnancy loss rates were 6.3%, 24.6%, 50% for the low-, intermediate- and high-risk categories, respectively (
Databáze: OpenAIRE