Short-Term Administration of Captopril and Nifedipine and Exercise-Induced Albuminuria in Normotensive Diabetic Patients With Early-Stage Nephropathy
| Autor: | Andrea Giustina, Simonetta Bossoni, Cravarezza P, Antonino Cimino, Andrea Caldonazzo, Gianni Giustina, Giuseppe Romanelli |
|---|---|
| Přispěvatelé: | Romanelli, G, Giustina, Andrea, Bossoni, S, Caldonazzo, A, Cimino, A, Cravarezza, P, Giustina, G. |
| Rok vydání: | 1990 |
| Předmět: |
Adult
Male medicine.medical_specialty Captopril Adolescent Nifedipine Endocrinology Diabetes and Metabolism Kidney Glomerulus Urology Administration Oral Angiotensin-Converting Enzyme Inhibitors Physical exercise Nephropathy Diabetic nephropathy Double-Blind Method Internal medicine Diabetes mellitus Internal Medicine medicine Albuminuria Humans Diabetic Nephropathies Exercise biology business.industry Angiotensin-converting enzyme Middle Aged medicine.disease Diabetes Mellitus Type 1 Blood pressure Endocrinology Diabetes Mellitus Type 2 biology.protein Female business medicine.drug |
| Zdroj: | Diabetes. 39:1333-1338 |
| ISSN: | 1939-327X 0012-1797 |
| DOI: | 10.2337/diab.39.11.1333 |
| Popis: | Recent studies have demonstrated that short-term angiotensin converting enzyme (ACE) inhibition with captopril can reduce urinary albumin excretion rate (UAER) after exercise in normotensive diabetic patients with early-stage nephropathy. The aim of this study was to investigate whether this effect of ACE inhibition was due to a systemic hypotensive action or a specific action at the intrarenal level. Thus, we compared the acute effects of captopril and the Ca2+-channel blocker nifedipine on exercise-induced UAER in normotensive (blood pressure |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|