Influence of thrombolysis on signal-averaged electrocardiogram and late arrhythmic events after acute myocardial infarction
| Autor: | Roberto Bonelli, Francesco Santoro, Roberto F.E. Pedretti, Bruno Carù, Mario D. Etro, Adelia Gementi, Claudio Anzà, Antonio Laporta, Enrica Colombo, Franco Maslowsky |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Myocardial Infarction Group A Group B Electrocardiography Internal medicine medicine Humans Thrombolytic Therapy Myocardial infarction Chi-Square Distribution business.industry Incidence (epidemiology) Arrhythmias Cardiac Signal Processing Computer-Assisted Thrombolysis Ventricular late potentials Middle Aged medicine.disease Signal-averaged electrocardiogram Logistic Models Multivariate Analysis Cardiology Electrocardiography Ambulatory Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | The American journal of cardiology. 69(9) |
| ISSN: | 0002-9149 |
| Popis: | The influence of intravenous thrombolysis on both prevalence of ventricular late potentials and incidence of late arrhythmic events was evaluated in 174 consecutive patients surviving a first acute myocardial infarction; 106 patients (61%) received thrombolysis (group A) and 68 (34%) had conventional therapy (group B). In group A, 18 patients (17%) had late potentials compared with 23 (34%) in group B (p less than 0.05); mean left ventricular ejection fraction was not different (0.50 +/- 0.09 vs 0.50 +/- 0.10; p = not significant [NS]). Of 63 patients who underwent coronary arteriography because of postinfarction ischemia, 28 (44%) had a closed infarct-related artery; of these, 11 (39%) had late potentials compared with 3 of 35 (9%) with a patent artery (p less than 0.01). Mean left ventricular ejection fraction was not significantly different between the 2 groups (0.49 +/- 0.09 vs 0.53 +/- 0.09; p = NS). At a mean follow-up of 14 +/- 8 months, 8 of 161 patients (5%) had a late arrhythmic event; 6 of 8 (75%) with and 28 of 153 (18%) without events had late potentials (p less than 0.001). In group A, 4 of 99 patients (4%) had events compared with 4 of 62 (6%) in group B (p = NS, relative risk 1.6). Of 24 patients with anterior wall AMI and left ventricular dyskinesia, 6 events occurred. In this group of patients, a higher rate of events was observed (25%); 3 of 16 (19%) treated with thrombolysis had an event compared with 3 of 8 (37%) treated conventionally (p = NS, relative risk 2.6).(ABSTRACT TRUNCATED AT 250 WORDS) |
| Databáze: | OpenAIRE |
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