Characteristics of adult patients with atrial septal defects presenting with paradoxical embolism
| Autor: | Frank E. Silvestry, Howard C. Herrmann, Rhuna Shen, Amr Bannan |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male Cardiac Catheterization medicine.medical_specialty Adolescent Septal Occluder Device medicine.medical_treatment Foramen Ovale Patent Heart Septal Defects Atrial Atrial septal defects Young Adult Sex Factors Paradoxical embolism Risk Factors Internal medicine medicine Humans Radiology Nuclear Medicine and imaging Stroke Aged Retrospective Studies Cardiac catheterization Aged 80 and over Heart septal defect business.industry Incidence Age Factors Hemodynamics General Medicine Middle Aged Pennsylvania medicine.disease Surgery Treatment Outcome Embolism Patent foramen ovale Cardiology Female Cardiology and Cardiovascular Medicine business Embolism Paradoxical |
| Zdroj: | Catheterization and Cardiovascular Interventions. 74:1066-1069 |
| ISSN: | 1522-726X 1522-1946 |
| DOI: | 10.1002/ccd.22170 |
| Popis: | Background: The association between patent foramen ovale (PFO), atrial septal aneurysm, and cryptogenic stroke due to paradoxical embolism has been established. The correlation between atrial septal defect (ASD) in adults and paradoxical embolism is less well defined. Methods: We examined our single center experience with 329 adult patients undergoing percutaneous device closure of interatrial communication defects to identify clinical and morphologic differences among adult patients with ASDs who presented with or without paradoxical embolism. Comparison was made with patients with PFO. Results: Although a significant left-to-right shunt was the predominant indication for ASD closure, 20 patients (14%) presented with a paradoxical embolism. These patients tended to be younger and had smaller defects (both by size and shunt ratio) than ASD patients without paradoxical embolism, and were more likely to be female than PFO patients. Conclusions: The incidence of adult patients with ASD who presented with paradoxical embolism is higher than expected and suggests that this diagnosis should be considered in patients with cryptogenic stroke. © 2009 Wiley-Liss, Inc. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text