Evaluation of serum cathepsin B, D, and L concentrations in women with late-onset preeclampsia
| Autor: | Gokce Anik Ilhan, Begum Yildizhan |
|---|---|
| Přispěvatelé: | Ilhan, Gokce Anik, Yildizhan, Begum |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
cathepsin D lcsh:Medicine Cathepsin D lcsh:Gynecology and obstetrics Cathepsin B Preeclampsia cathepsin L Cathepsin L preeclampsia Internal medicine medicine Clinical Investigation lcsh:RG1-991 reproductive and urinary physiology biology business.industry lcsh:R Significant difference Obstetrics and Gynecology Serum concentration medicine.disease Late onset preeclampsia female genital diseases and pregnancy complications CYSTEINE CATHEPSINS PROTEASES Endocrinology biology.protein business |
| Zdroj: | Turkish Journal of Obstetrics and Gynecology Turkish Journal of Obstetrics and Gynecology, Vol 16, Iss 2, Pp 91-94 (2019) |
| Popis: | Objective: The aim of the study was to assess serum cathepsin B, D, and L concentrations in women with late-onset preeclampsia. Materials and Methods: One hundred forty pregnant women were enrolled in the study, of which 100 subjects were preeclamptic and 40 were healthy controls. Serum concentrations of cathepsin B, D, and L were measured and compared between the preeclamptic and control groups. Results: Cathepsin B and D concentrations were significantly higher in the preeclamptic group compared with the control group. There was no statistically significant difference between the groups in terms of cathepsin L concentrations. Cathepsin B concentrations were significantly higher in women with preeclampsia with severe features compared with those with preeclampsia alone. Conclusion: Women with late-onset preeclampsia have significantly higher serum cathepsin B and D concentrations than controls. Cathepsin B and D may be promising biomarkers in women with late-onset preeclampsia. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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