Chiral Recognition of Amino Acids and Dipeptides by a Water-Soluble Zinc Porphyrin
| Autor: | Naoki Sakura, Hiroki Munakata, Hiroyasu Imai, Yoshio Uemori |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
inorganic chemicals
Steric effects Circular dichroism Metalloporphyrins Stereochemistry Molecular Conformation Stereoisomerism Inorganic Chemistry chemistry.chemical_compound polycyclic compounds heterocyclic compounds Amino Acids Physical and Theoretical Chemistry Chromatography High Pressure Liquid chemistry.chemical_classification Aqueous solution Chemistry Circular Dichroism Spectrum Analysis organic chemicals Water Dipeptides Porphyrin Amino acid Solutions Chiral column chromatography Solubility health occupations Thermodynamics Enantiomer |
| Zdroj: | Inorganic Chemistry. 43:1211-1213 |
| ISSN: | 1520-510X 0020-1669 |
| DOI: | 10.1021/ic0302837 |
| Popis: | A chiral water-soluble zinc porphyrin was optically resolved on a chiral HPLC column, and the binding of chiral amino acids and peptides to each of the enantiomers was examined spectrophotometrically in basic aqueous solution. The binding data apparently indicated that the zinc porphyrin has chiral selectivity for amino acids and dipeptides. This was reasonably explained in terms of the triple cooperation of coordination, Coulomb, and steric interactions of the chiral amino carboxylates with the porphyrin. A compensatory relationship among the thermodynamic parameters for chiral recognition was also shown. |
| Databáze: | OpenAIRE |
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