Alkaline Water and Longevity: A Murine Study
| Autor: | Livio Corain, Luigi Salmaso, Milo Terzo, Vittorino Corraducci, Fabio Vianello, Emanuela Bonaiuto, Davide Baratella, Massimiliano Magro, Silvia Ferro |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
education.field_of_study Article Subject Ecology media_common.quotation_subject Aging factor Population Longevity lcsh:Other systems of medicine Alkaline water Biology lcsh:RZ201-999 Biological effect Andrology 03 medical and health sciences 030104 developmental biology Complementary and alternative medicine Survival study Statistical analysis education Histological examination media_common Research Article |
| Zdroj: | Evidence-based Complementary and Alternative Medicine : eCAM Evidence-Based Complementary and Alternative Medicine, Vol 2016 (2016) |
| ISSN: | 1741-427X |
| Popis: | The biological effect of alkaline water consumption is object of controversy. The present paper presents a 3-year survival study on a population of 150 mice, and the data were analyzed with accelerated failure time (AFT) model. Starting from the second year of life, nonparametric survival plots suggest that mice watered with alkaline water showed a better survival than control mice. Interestingly, statistical analysis revealed that alkaline water provides higher longevity in terms of “deceleration aging factor” as it increases the survival functions when compared with control group; namely, animals belonging to the population treated with alkaline water resulted in a longer lifespan. Histological examination of mice kidneys, intestine, heart, liver, and brain revealed that no significant differences emerged among the three groups indicating that no specific pathology resulted correlated with the consumption of alkaline water. These results provide an informative and quantitative summary of survival data as a function of watering with alkaline water of long-lived mouse models. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text