Visit-to-visit variability in systolic blood pressure is a novel risk factor for the progression of coronary artery calcification

Autor: Naoko Nakanishi, Naoto Nakamura, Muhei Tanaka, Ki-ichiro Tomiyasu, Shinobu Matsumoto, Koji Nakano, Hiroshi Okada, Goji Hasegawa, Yusuke Mineoka, Michiaki Fukui
Rok vydání: 2012
Předmět:
Zdroj: Hypertension research : official journal of the Japanese Society of Hypertension. 36(11)
ISSN: 1348-4214
Popis: Recent studies have suggested that variability in the systolic blood pressure (SBP) is a risk factor for cardiovascular disease (CVD). The aim of this study was to investigate the relationship between variability in the SBP and the progression of coronary artery calcification (CAC), which is a useful marker for CVD. We measured SBP in 164 consecutive patients at every visit over the course of a year and calculated the coefficient of variation and s.d. of the SBP. We performed a follow-up study using multislice computed tomography to assess the progression of the CAC score, the mean interval of which was 3.93 ± 1.36 years. We then evaluated the relationship between variability in the SBP and progression of the CAC score. The coefficient of variation for the SBP correlated positively with the progression of the CAC score (r=0.4382, P
Databáze: OpenAIRE