Repigmentation in vitiligo: position paper of the Vitiligo Global Issues Consensus Conference

Autor:	Tamio Suzuki, Davinder Parsad, Amit G. Pandya, John E. Harris, Charlotte Vrijman, Vaneeta Seth, Emily Yiping Gan, Sanjeev V. Mulekar, Yvon Gauthier, Prasad Kumarasinghe, Markus Böhm, Alain Taieb, Mauro Picardo, Ichiro Katayama, Iltefat H. Hamzavi, Boon Kee Goh, Tag S. Anbar, Thierry Passeron, Samia Esmat, Steven Tien Guan Thng, Richard A. Wittal, Cheng‐Che Eric Lan, Nanja van Geel, Viktoria Eleftheriadou, Julien Seneschal, Caio Cesar Silva de Castro, Laila Benzekri, M. Ramam, Henry W. Lim, Noufal Raboobee, Marwa Abdallah, Khaled Ezzedine, Marcel W. Bekkenk, Harvey Lui
Přispěvatelé:	Dermatology
Jazyk:	angličtina
Rok vydání:	2017
Předmět:	0301 basic medicine medicine.medical_specialty Consensus Treatment outcome Vitiligo Skin Pigmentation Dermatology General Biochemistry Genetics and Molecular Biology 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Wnt beta catenin Medicine Humans Medical physics business.industry Consensus conference Outcome measures Congresses as Topic medicine.disease 030104 developmental biology Treatment Outcome Oncology Position paper business
Zdroj:	Pigment cell & melanoma research, 30(1), 28-40. Wiley-Blackwell
ISSN:	1755-1471
DOI:	10.1111/pcmr.12561
Popis:	Summary The Vitiligo Global Issues Consensus Conference (VGICC), through an international e-Delphi consensus, concluded that “repigmentation” and “maintenance of gained repigmentation” are essential core outcome measures in future vitiligo trials. This VGICC position paper addresses these core topics in two sections and includes an atlas depicting vitiligo repigmentation patterns and color match. The first section delineates mechanisms and characteristics of vitiligo repigmentation and the second summarizes the outcomes of international meeting discussions and two e-surveys on vitiligo repigmentation, which had been carried out over three years. Treatment is defined as successful if repigmentation exceeds 80% and at least 80% of the gained repigmentation is maintained for over 6 months. No agreement was found on the best outcome measure for assessing target or global repigmentation, therefore highlighting the limitations of e-surveys in addressing clinical measurements. Until there is a clear consensus, existing tools should be selected according to the specific needs of each study. A workshop will be conducted to address the remaining issues so as to achieve a consensus. This article is protected by copyright. All rights reserved.
Databáze:	OpenAIRE
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