Effects of D-allulose on glucose metabolism after the administration of sugar or food in healthy dogs
| Autor: | Naohito Nishii, Tatsuya Matsubara, Hitoshi Kitagawa, Satoshi Takashima, Masaaki Tokuda, Toru Nomizo |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Blood Glucose medicine.medical_specialty insulin medicine.medical_treatment Fructose Carbohydrate metabolism Impaired glucose tolerance 03 medical and health sciences chemistry.chemical_compound Dogs Internal medicine Diabetes mellitus Blood plasma medicine Internal Medicine Animals Hypoglycemic Agents Maltose D-allulose rare sugar General Veterinary Full Paper business.industry Insulin Metabolism medicine.disease Rare sugar Postprandial Period Biotechnology 030104 developmental biology Endocrinology Glucose chemistry Food dog business |
| Zdroj: | The Journal of Veterinary Medical Science |
| ISSN: | 1347-7439 |
| Popis: | D-allulose is a C-3 epimer of D-fructose and has recently been investigated for its hypoglycemic effects. In the present study, the effects of D-allulose on glucose metabolism were evaluated in healthy dogs administrated sugar or food. The oral administrations of D-allulose decreased plasma glucose concentrations after oral glucose or maltose administration, with a diminished plasma insulin rise. The glucose suppressive effect of D-allulose was also observed after intravenous glucose administrations without increase in plasma insulin concentration. In contrast, D-allulose showed no effect on plasma glucose and insulin concentrations after feeding. The present results suggest that D-allulose administration may be beneficial in dogs with impaired glucose tolerance. Further studies investigating the therapeutic efficacy of D-allulose in diabetic dogs are required. |
| Databáze: | OpenAIRE |
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