First person experience of threat modulates cortical network encoding human peripersonal space
| Autor: | Beatrice de Gelder, Aline W. de Borst, Maria V. Sanchez-Vives, Mel Slater |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0303 health sciences
Brain activity and meditation Perspective (graphical) Parietal lobe Space (commercial competition) Social relation 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Cortex (anatomy) Synchronization (computer science) medicine Psychology Priming (psychology) 030217 neurology & neurosurgery 030304 developmental biology Cognitive psychology |
| DOI: | 10.1101/314971 |
| Popis: | Peripersonal space is the area directly surrounding the body, which supports object manipulation and social interaction, but is also critical for threat detection. In the monkey, ventral premotor and intraparietal cortex support initiation of defensive behavior. However, the brain network that underlies threat detection in human peripersonal space still awaits investigation. We combined fMRI measurements with a preceding virtual reality training from either first or third person perspective to manipulate whether approaching human threat was perceived as directed to oneself or another. We found that first person perspective increased body ownership and identification with the virtual victim. When threat was perceived as directed towards oneself, synchronization of brain activity in the human peripersonal brain network was enhanced and connectivity increased from premotor and intraparietal cortex towards superior parietal lobe. When this threat was nearby, synchronization also occurred in emotion-processing regions. Priming with third person perspective reduced synchronization of brain activity in the peripersonal space network and increased top-down modulation of visual areas. In conclusion, our results showed that after first person perspective training peripersonal space is remapped to the virtual victim, thereby causing the fronto-parietal network to predict intrusive actions towards the body and emotion-processing regions to signal nearby threat. |
| Databáze: | OpenAIRE |
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