Syntheses of 1-hydroxytryptamines and serotonins having fattyacyl or (E)-3-phenylpropenoyl derivatives as a Nb-substituent, and a novel homologation on the 3-substituent of the 1-hydroxytryptamines upon treatment with diazomethane

Autor:	Masanori Somei, Harunobu Morikawa, Fumio Yamada, Koji Yamada
Jazyk:	angličtina
Rok vydání:	1998
Předmět:	Pharmacology chemistry.chemical_compound chemistry Diazomethane Organic Chemistry Substituent Organic chemistry Analytical Chemistry
Zdroj:	Scopus-Elsevier
Popis:	金沢大学大学院自然科学研究科生理活性物質科学 金沢大学薬学部 1-Hydroxytryptamines (6a-f) having (E)-3-phenyl-, (E)-3-(4-hydroxyphenyl)-, (E)-3-(4-hydroxy-3-methoxyphenyl)propenoyl, octanoyl, hexadecanoyl, and docosanoyl group as a Nb-substituent are prepared for the first time. Preparations of serotonins (2a-c, e) from the corresponding 1-hydroxytryptamines (6a-c, e) are also reported. A novel homologation on the 3-substituent of 1-hydroxytryptamines is discovered upon treatment with diazomethane in chloroform or dichloromethane.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::279132adca4a6f0cf0949e5d4e612536 http://hdl.handle.net/2297/4348 Zobrazit plný text záznamu