Costs and Resource Utilization for Diagnosis and Treatment During the Initial Year in a European Inflammatory Bowel Disease Inception Cohort:An ECCO-EpiCom Study
| Autor: | Jens Kjeldsen, Ebbe Langholz, Svetlana Turcan, Sven Almer, Shaji Sebastian, Y. Bailey, Jónger Olsen, Doron Schwartz, Niels Thorsgaard, Selwyn Odes, Daniela Lazăr, Riina Salupere, Susanne Krabbe, Michael Friger, Juan R. Pineda, Adrian Goldis, Konstantinnos H. Katsanos, Her-Hsin Tsai, Vibeke Andersen, Søren Avnstrøm, Hillel Vardi, L. Barros, Laimas Virginijus Jonaitis, I. Kaimakliotis, Angelo De Padova, Limas Kupčinskas, S. Cukovic-Cavka, Dan Greenberg, Jens Frederik Dahlerup, Colm A. OʼMorain, Dana Duricova, Peter L. Lakatos, Epameinondas V. Tsianos, Inna Nikulina, Laszlo Lakatos, Pekka Collin, Alberto Fernandez, Fernando Magro, K. Ladefoged, K R Nielsen, Natalia Pedersen, Johan Burisch, Pia Manninen, Jonas Halfvarson, Marko Brinar, Guido Lupinacci, Pia Munkholm, Elena Belousova, Martin Bortlik, Ida Vind, Olga Shonová |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Male
Adult medicine.medical_specialty Time Factors Adolescent Epidemiology Population Inflammatory bowel disease Gastroenterology Cohort Studies Young Adult Internal medicine Surveys and Questionnaires medicine Immunology and Allergy Humans education Economics of IBD therapies Aged Health Resources/statistics & numerical data Aged 80 and over education.field_of_study Crohn's disease business.industry Standard treatment Inflammatory Bowel Diseases/diagnosis Health Care Costs Middle Aged Inflammatory Bowel Diseases medicine.disease Prognosis Ulcerative colitis Eastern european Europe Outcomes research Cohort Health Resources Female business Health Care Costs/trends Cohort study Follow-Up Studies |
| Zdroj: | Burisch, J, Vardi, H, Pedersen, N, Brinar, M, Cukovic-Cavka, S, Kaimakliotis, I, Duricova, D, Bortlik, M, Shonová, O, Vind, I, Avnstrøm, S, Thorsgaard, N, Krabbe, S, Andersen, V, Dahlerup, J F, Kjeldsen, J, Salupere, R, Olsen, J, Nielsen, K R, Manninen, P, Collin, P, Katsanos, K H, Tsianos, E V, Ladefoged, K, Lakatos, L, Bailey, Y, OʼMorain, C, Schwartz, D, Lupinacci, G, De Padova, A, Jonaitis, L, Kupcinskas, L, Turcan, S, Barros, L, Magro, F, Lazar, D, Goldis, A, Nikulina, I, Belousova, E, Fernandez, A, Pineda, J R, Almer, S, Halfvarson, J, Tsai, H-H, Sebastian, S, Friger, M, Greenberg, D, Lakatos, P L, Langholz, E, Odes, S & EpiCom Group 2015, ' Costs and Resource Utilization for Diagnosis and Treatment During the Initial Year in a European Inflammatory Bowel Disease Inception Cohort : An ECCO-EpiCom Study ', Inflammatory Bowel Diseases, vol. 21, no. 1, pp. 121-131 . https://doi.org/10.1097/MIB.0000000000000250 Burisch, J, Vardi, H, Pedersen, N, Brinar, M, Cukovic-Cavka, S, Kaimakliotis, I, Duricova, D, Bortlik, M, Shonová, O, Vind, I, Avnstrøm, S, Thorsgaard, N, Krabbe, S, Andersen, V, Dahlerup, J F, Kjeldsen, J, Salupere, R, Olsen, J, Nielsen, K R, Manninen, P, Collin, P, Katsanos, K H, Tsianos, E V, Ladefoged, K, Lakatos, L, Bailey, Y, OʼMorain, C, Schwartz, D, Lupinacci, G, De Padova, A, Jonaitis, L, Kupcinskas, L, Turcan, S, Barros, L, Magro, F, Lazar, D, Goldis, A, Nikulina, I, Belousova, E, Fernandez, A, Pineda, J R, Almer, S, Halfvarson, J, Tsai, H-H, Sebastian, S, Friger, M, Greenberg, D, Lakatos, P L, Langholz, E, Odes, S & EpiCom Group 2015, ' Costs and resource utilization for diagnosis and treatment during the initial year in a European inflammatory bowel disease inception cohort : an ECCO-EpiCom Study ', Inflammatory Bowel Diseases, vol. 21, no. 1, pp. 121-31 . https://doi.org/10.1097/MIB.0000000000000250 |
| Popis: | BACKGROUND: No direct comparison of health care cost in patients with inflammatory bowel disease across the European continent exists. The aim of this study was to assess the costs of investigations and treatment for diagnostics and during the first year after diagnosis in Europe.METHODS: The EpiCom cohort is a prospective population-based inception cohort of unselected inflammatory bowel disease patients from 31 Western and Eastern European centers. Patients were followed every third month from diagnosis, and clinical data regarding treatment and investigations were collected. Costs were calculated in euros (€) using the Danish Health Costs Register.RESULTS: One thousand three hundred sixty-seven patients were followed, 710 with ulcerative colitis, 509 with Crohn's disease, and 148 with inflammatory bowel disease unclassified. Total expenditure for the cohort was €5,408,174 (investigations: €2,042,990 [38%], surgery: €1,427,648 [26%], biologicals: €781,089 [14%], and standard treatment: €1,156,520 [22%)]). Mean crude expenditure per patient in Western Europe (Eastern Europe) with Crohn's disease: investigations €1803 (€2160) (P = 0.44), surgery €11,489 (€13,973) (P = 0.14), standard treatment €1027 (€824) (P = 0.51), and biologicals €7376 (€8307) (P = 0.31). Mean crude expenditure per patient in Western Europe (Eastern Europe) with ulcerative colitis: investigations €1189 ( €1518) (P < 0.01), surgery €18,414 ( €12,395) (P = 0.18), standard treatment €896 ( €798) (P < 0.05), and biologicals €5681 ( €72) (P = 0.51).CONCLUSIONS: In this population-based unselected cohort, costs during the first year of disease were mainly incurred by investigative procedures and surgeries. However, biologicals accounted for >15% of costs. Long-term follow-up of the cohort is needed to assess the cost-effectiveness of biological agents. |
| Databáze: | OpenAIRE |
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