Obstructive Sleep Apnea Syndrome as an Important Risk Factor in Severe Covid-19 Disease

Autor:	Cuspineda Elena, DeFina Phillip A, Chinchilla Mauricio, Machado Calixto, Machado Yazmina, Machado Yanín
Rok vydání:	2020
Předmět:	medicine.medical_specialty Coronavirus disease 2019 (COVID-19) business.industry Disease medicine.disease Obesity respiratory tract diseases Obstructive sleep apnea Coronary artery disease Internal medicine Heart failure Diabetes mellitus medicine Cardiology Risk factor business
Zdroj:	Journal of Clinical Anesthesia and Pain Management. 4
ISSN:	2578-658X
DOI:	10.36959/377/347
Popis:	OSAS has been considered by some authors an important risk factor for severe Covid-19. Risk factors for mortality in COVID-19, such as cardiovascular and cerebrovascular complications or comorbidities, for example hypertension, heart failure, coronary artery disease, cerebrovascular diseases, diabetes mellitus, and obesity are commonly seen in OSAS patients. SARS-CoV-2 uses the ACE2 receptor for host cell entry, and augmented expression of ACE and dysregulation of the renin-angiotensin system in untreated OSAS patients, due to chronic intermittent hypoxia, has been shown.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::278878d8bbabc033d9696cdd5b405013 https://doi.org/10.36959/377/347 Zobrazit plný text záznamu