Numerical simulation of the aqueous humor flow in the eye drainage system; a healthy and pathological condition comparison
| Autor: | J. Naude, C. Escobar del Pozo, A. Brambila Solorzano, G.J. Martínez Sánchez, J.A. Rocha Medina |
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| Rok vydání: | 2020 |
| Předmět: |
Intraocular pressure
Materials science Buoyancy genetic structures Anterior Chamber 0206 medical engineering Biomedical Engineering Biophysics Glaucoma 02 engineering and technology engineering.material Aqueous Humor 03 medical and health sciences 0302 clinical medicine Trabecular Meshwork Parasitic drag otorhinolaryngologic diseases medicine Shear stress Humans Intraocular Pressure Computer simulation Mechanics medicine.disease 020601 biomedical engineering Nusselt number eye diseases stomatognathic diseases medicine.anatomical_structure engineering sense organs Trabecular meshwork 030217 neurology & neurosurgery |
| Zdroj: | Medical Engineering & Physics. 83:82-92 |
| ISSN: | 1350-4533 |
| DOI: | 10.1016/j.medengphy.2020.07.010 |
| Popis: | The present work describes the motion of aqueous humor through the anterior chamber and the trabecular drainage system, considering several distributions of the collector channels. The 3D computational model, implemented into the open-source software, was reconstructed from an optical coherence tomography. The model has been employed to simulate the aqueous humor dynamics considering buoyancy effects. The presence of the anterior chamber, the trabecular meshwork, and the Schlemm's canal were taken into consideration with 14 different distributions of collector channels. The influence of collector channels position on the intraocular pressure and shear stress has been analyzed, for a healthy and a glaucomatous condition. Aqueous humor velocity, pressure, temperature, wall shear stress, skin friction coefficient and Nusselt number, are presented for the different cases. The results indicate that the position of the collector channels has a strong influence on the wall shear stress on the Schlemm's canal and collector channels. |
| Databáze: | OpenAIRE |
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