Accumulation of neurotoxic organochlorines and trace elements in brain of female European eel (Anguilla anguilla)
| Autor: | Claude Belpaire, Cathy Debier, Patrick Kestemont, J-P Thomé, M Thonon, Jean-François Rees, Chloé Bonnineau, Delphine Scaion, M Leermaker, Benjamin Lemaire, Y Gao, Frédéric Silvestre |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Health Toxicology and Mutagenesis chemistry.chemical_element 010501 environmental sciences Toxicology 01 natural sciences 03 medical and health sciences chemistry.chemical_compound Belgium Rivers medicine Hydrocarbons Chlorinated Animals Tissue Distribution PCBs Relative species abundance Arsenic 0105 earth and related environmental sciences Pharmacology Pollutant Cadmium Neurotoxicity Eel Brain Aquatic animal General Medicine Mercury medicine.disease Anguilla Mercury (element) Trace Elements 030104 developmental biology chemistry Metals Environmental chemistry Organochlorine pesticides Female Xenobiotic Water Pollutants Chemical Environmental Monitoring |
| Zdroj: | Environmental Toxicology and Pharmacology. 45:346-355 |
| ISSN: | 1382-6689 |
| DOI: | 10.1016/j.etap.2016.06.009 |
| Popis: | Xenobiotics such as organochlorine compounds (OCs) and metals have been suggested to play a significant role in the collapse of European eel stocks in the last decades. Several of these pollutants could affect functioning of the nervous system. Still, no information is so far available on levels of potentially neurotoxic pollutants in eel brain. In present study, carried out on female eels caught in Belgian rivers and canals, we analyzed brain levels of potentially-neurotoxic trace elements (Ag, Al, As, Cd, Co, Cr, Cu, Fe, Hg, MeHg, Mn, Ni, Pb, Sn, Sb, Zn) and OCs (Polychlorinated biphenyls, PCBs; Hexachlorocyclohexanes, HCHs; Dichlorodiphenyltrichloroethane and its metabolites, DDTs). Data were compared to levels in liver and muscle tissues. Eel brain contained very high amounts of OCs, superior to those found in the two other tissues. Interestingly, the relative abundance of PCB congeners markedly differed between tissues. In brain, a predominance of low chlorinated PCBs was noted, whereas highly chlorinated congeners prevailed in muscle and liver. HCHs were particularly abundant in brain, which contains the highest amounts of β-HCH and ϒ-HCH. p,p ’-DDTs concentration was similar between brain and muscle (i.e., about twice that of liver). A higher proportion of p,p ’ - DDT was noticed in brain. Except for Cr and inorganic Hg, all potentially neurotoxic metals accumulated in brain to levels equal to or lower than hepatic levels. Altogether, results indicate that eel brain is an important target for organic and, to a lesser extent, for inorganic neurotoxic pollutants. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect