Pituitary cretinism in two sisters
| Autor: | H Kohno, M Ootsuka, N Watanabe, N Gohya, M Kajiwara |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1980 |
| Předmět: |
medicine.medical_specialty
endocrine system Triiodothyronine endocrine system diseases business.industry Infant Thyrotropin TSH Deficiency medicine.disease Congenital hypothyroidism Pedigree Endocrinology Internal medicine Pediatrics Perinatology and Child Health medicine Congenital Hypothyroidism Humans Female business Cretinism hormones hormone substitutes and hormone antagonists Hormone Research Article |
| Popis: | Two sisters with cretinism are reported. Each showed low levels of serum triiodothyronine, thyroxine, and thyroid-stimulating hormone (TSH). In the elder sister, serum TSH did not increase after administration of thyrotropin-releasing hormone. We conclude that cretinism in these 2 sisters was due to TSH deficiency. This is the second report of 'familial' pituitary cretinism (TSH-deficient congenital hypothyroidism). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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