Lymphocyte subpopulations in mother and newborn: correlation with sex of the newborn and number of pregnancies
| Autor: | D. Aloni, J. Landmann, J.G. Goldman, J. Notmann, I. Halbrecht, F. Dulitzky, L. Komlos |
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| Rok vydání: | 1989 |
| Předmět: |
Male
medicine.medical_specialty Time Factors T cell Lymphocyte T-Lymphocytes Physiology Fluorescent Antibody Technique chemical and pharmacologic phenomena Correlation Lymphocyte subpopulations Pregnancy Internal medicine medicine Humans Labor Obstetric biology Infant Newborn Obstetrics and Gynecology Antibodies Monoclonal hemic and immune systems medicine.disease Parity Endocrinology medicine.anatomical_structure Reproductive Medicine biology.protein Gestation Female Sex Antibody Parity (mathematics) |
| Zdroj: | Gynecologic and obstetric investigation. 27(3) |
| ISSN: | 0378-7346 |
| Popis: | T cell subsets were defined with monoclonal antibodies of the OKT series, OKT3, OKT4 and OKT8, in 23 male and 22 female newborns and in their mothers 4–10 h after delivery. The data were compared and statistically evaluated between mother and newborn, between male and female newborns as well as between parity groups. The results indicate that the distribution of OKT4 and OKT8+ cells is different in mother and newborn and a significantly increased percentage of OKT4+ cells and a significantly decreased percentage of OKT3+ cells was observed in newborns as compared to their mothers after the first and second delivery. For maternal cells from male as compared to female newborns the percentage of OKT4+ was significantly decreased after the second delivery. OKT8+ cells in the mother were significantly decreased after the second as well as after three or more deliveries of male as compared to female newborns. With increasing parity the percentage of OKT3+, OKT4+ and OKT8+ cells decreased slowly for both sexes and the difference was significant between primi- and multiparae. The present findings suggest a possible role of the newborn sex and of parity in the distribution of specific T cell subsets in mother and newborn shortly after delivery. |
| Databáze: | OpenAIRE |
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