A Case of Docetaxel-Induced Erythrodysesthesia
| Autor: | Masafumi Kadota, Mayumi Katoh, Youichi Nishimura |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Male
medicine.medical_specialty Erythema medicine.medical_treatment Docetaxel Hand Dermatoses Dermatology Diagnosis Differential Lesion medicine Humans Facial erythema skin and connective tissue diseases Acral erythema Aged Foot Dermatoses Chemotherapy integumentary system business.industry Prostatic Neoplasms General Medicine Antineoplastic Agents Phytogenic Surgery Taxoids Drug Eruptions medicine.symptom business Facial Dermatoses medicine.drug |
| Zdroj: | The Journal of Dermatology. 31:403-406 |
| ISSN: | 0385-2407 |
| DOI: | 10.1111/j.1346-8138.2004.tb00692.x |
| Popis: | Chemotherapy-induced acral erythema (CIAE) is a rare cutaneous reaction to high-dose chemotherapy, clinically featuring painful erythema on the palms and soles. Docetaxel (Taxotere), an anticancer agent, is known to cause various reactions, including CIAE. We experienced a case of docetaxel-induced acral erythema with facial edematous erythema that coincidentally emerged and regressed with appearance and disappearance of the acral lesions. Docetaxel-induced acral erythema exhibits a widespread distribution and intense sensations of intolerable pain and numbness. Therefore, some authors use the term erythrodysesthesia instead of acral erythema. We speculated that the facial erythema might be part of the spectrum of erythrodysesthesia. Our case was finally diagnosed as decetaxel-induced erythrodysesthesia. Although CIAE is self-limiting, the patients frequently require treatment because of intolerable pain. Reported treatments for CIAE include topical or systemic steroids, elevation of the legs, and application of cold compression to the lesion. In our case, application of a steroid ointment with the occlusive dressing technique (ODT) alleviated the clinical manifestations and was also prophylactic for the erythrodysesthesia. |
| Databáze: | OpenAIRE |
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