Use of liothyronine (L-T3) as an augmentation therapy for depression during pregnancy
| Autor: | Vishal Bhella, Divya Garg |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Adult
Pediatrics medicine.medical_specialty Levothyroxine Thyroid function tests 03 medical and health sciences 0302 clinical medicine Pregnancy medicine Humans 030212 general & internal medicine Liothyronine Triiodothyronine Unexpected Outcome (Positive or Negative) Including Adverse Drug Reactions medicine.diagnostic_test business.industry Depression Thyroid disease Thyroid General Medicine medicine.disease Pregnancy Complications Thyroxine medicine.anatomical_structure Chemotherapy Adjuvant Female business 030217 neurology & neurosurgery Selective Serotonin Reuptake Inhibitors medicine.drug Hormone |
| Zdroj: | BMJ Case Rep |
| ISSN: | 1757-790X |
| Popis: | The thyroid hormone triiodothyronine (T3) can be used as an augmentation therapy for depression. This case involves a patient who had been initiated on liothyronine (L-T3) for this purpose and subsequently became pregnant. The exogenous T3 affected maternal thyroid hormone production, including suppression of her thyroxine (T4) levels. In pregnancy, maternal T4 is important for fetal neurodevelopment. Accordingly, use of exogenous T3 for adjunct treatment of depression in pregnant patients or those planning pregnancy requires careful laboratory monitoring of thyroid function tests. In this case, L-T3 was discontinued and the patient was eventually started on levothyroxine (L-T4) and went on to have an uneventful pregnancy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|