Angiotensin-converting Enzyme in Crohn’s Disease and Ulcerative Colitis
| Autor: | Joan Friedland, Michael R. Simon, Emanuel Silverstein, Joel V. Weinstock, Sidney M. Fierst |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Adult
Male medicine.medical_specialty Colon Prednisolone Ileum Peptidyl-Dipeptidase A Gastroenterology Inflammatory bowel disease Crohn Disease Internal medicine medicine Humans Ileitis Colitis Crohn's disease biology business.industry Angiotensin-converting enzyme General Medicine Middle Aged medicine.disease Ulcerative colitis digestive system diseases medicine.anatomical_structure biology.protein Colitis Ulcerative Female Sarcoidosis business |
| Zdroj: | American Journal of Clinical Pathology. 75:175-178 |
| ISSN: | 1943-7722 0002-9173 |
| DOI: | 10.1093/ajcp/75.2.175 |
| Popis: | The relationship between serum angiotensin-converting enzyme activity and inflammatory bowel disease was investigated in 37 patients who had Crohn's disease, 31 patients who had ulcerative colitis, and 104 control subjects. The enzyme activity tended to be depressed in Crohn's ileitis (P less than 0.05) and colitis, but not in Crohn's ileocolitis and ulcerative colitis. No increase in enzyme activity was observed in Crohn's disease ileum or colon or in ulcerative colitis colon. The granulomatous inflammation in Crohn's disease differs from that in sarcoidosis, in which striking elevation of angiotensin-converting enzyme is present in granulomatous tissue and frequently in serum. |
| Databáze: | OpenAIRE |
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