Hyperamylasemia due to macroamylasemia in adult gluten enteropathy
| Autor: | E. Coslovich, A. Giudici, R. Bruno, G. Serricchio, G. Bonetti, G. B. Vadacca, M. Bettonagli, R. Moratti |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Adult
Diet therapy Macromolecular Substances Clinical Biochemistry Macroamylasemia digestive system Coeliac disease Gliadin medicine Humans Enteropathy Amylase chemistry.chemical_classification biology business.industry nutritional and metabolic diseases General Medicine medicine.disease Gluten digestive system diseases Celiac Disease chemistry Anti-gliadin antibodies Immunology Amylases biology.protein Hyperamylasemia Female business |
| Zdroj: | Scandinavian journal of clinical and laboratory investigation. 57(3) |
| ISSN: | 0036-5513 |
| Popis: | We report hyperamylasemia due to macroamylasemia in a 33-year-old-woman with gluten enteropathy. Macroamylasemia was demonstrated by precipitation of 97% of amylase activity with PEG 6000. It was associated with increased serum IgA, with elevated values of specific IgA antibodies against alpha-gliadin and with a high titre of IgA anti-endomysium antibodies. Macroamylasemia disappeared after 2 months of a strict gluten-free diet. These data suggest that the increased IgA concentration in adult gluten enteropathy led to increased macroamylase formation. |
| Databáze: | OpenAIRE |
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