Rate-dependent QRS prolongation during exercise testing associated with hyperkalemia
Autor: | Masao Nakagawa, Kazuya Ishibashi, Natsuya Keira, Masaki Tsukamoto, Satoshi Hirasaki, Hiroaki Matsubara, Norifumi Urao, Masayuki Hyogo, Hirokazu Shiraishi, Takeshi Shirayama |
---|---|
Rok vydání: | 2004 |
Předmět: |
Male
medicine.medical_specialty Hyperkalemia Ischemia Mexiletine Electrocardiography QRS complex Heart Rate Internal medicine Heart rate medicine Humans cardiovascular diseases Aged business.industry Sodium channel nutritional and metabolic diseases medicine.disease Ventricular Premature Complexes Stenosis medicine.anatomical_structure Ventricle Anesthesia Exercise Test Cardiology medicine.symptom Cardiology and Cardiovascular Medicine business Anti-Arrhythmia Agents Sodium Channel Blockers medicine.drug |
Zdroj: | Journal of Electrocardiology. 37:241-245 |
ISSN: | 0022-0736 |
DOI: | 10.1016/j.jelectrocard.2004.02.006 |
Popis: | The present case showed gradual increase of QRS duration from 100 ms up to 180msec during an ergometer exercise test along with the heart rate increase. After exercise, QRS duration shortened and normalized. Laboratory test showed hyperkalemia (K = 8.0 mEq/l). T1 myocardial scintigraphy revealed exercise-induced transient ischemia in posterolateral region of left ventricle. Coronary angiography showed significant stenosis in the distal portion of left circumflex coronary artery. The increase of QRS duration was possibly due to the combination of hyperkalemia and the effect of mexiletine. The rate dependent blocking effect on sodium channel of mexiletine might be intensified under hyperkalemia. |
Databáze: | OpenAIRE |
Externí odkaz: |