Malignant pleural mesothelioma and its management
| Autor: | AE Martin-Ucar, M Daunt, M Malik |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Perioperative management business.industry Pleural mesothelioma medicine.medical_treatment respiratory system Decortication medicine.disease_cause medicine.disease Asbestos respiratory tract diseases Surgery medicine.anatomical_structure Anesthesiology and Pain Medicine medicine Pericardium Mesothelioma business Pleurectomy Survival rate |
| Zdroj: | BJA Education. 15:242-247 |
| ISSN: | 2058-5357 2058-5349 |
| DOI: | 10.1093/bjaed/mku040 |
| Popis: | Key points Malignant mesothelioma is a tumour of the mesothelial cells which occurs in the pleura in up to 90% of all cases, but can also occur in the peritoneum, pericardium, and testes. The term ‘mesothelioma’ is usually accepted as being synonymous with malignant mesothelioma. However, benign hyperplasia of mesothelial cells can also occur. This article describes the presentation and current treatment options for malignant pleural mesothelioma, focusing on the available surgical options, with particular emphasis on the perioperative management of radical pleurectomy and decortication. Recording of malignant mesothelioma cases began in 1968, and its incidence has been increasing; currently standing at 4.1 per 100 000.1 It is five times more likely to occur in men than women, which is attributed to its link with asbestos exposure and the male dominance in occupations where this occurs. Mesothelioma currently accounts for almost 1% of all deaths of men aged 75–79 yr, and the latest UK figures show that the overall number of mesothelioma deaths per year has increased from 153 in 1968 to 2347 in 2010.1 The annual number of deaths is due to peak at almost 2500 by the year 2015, following which it should decrease rapidly. Deaths resulting from malignant mesothelioma must be reported to the Coroner in order to accurately record cases, and a Coroner's post-mortem is nearly always required. The 5 yr survival rate for patients with … |
| Databáze: | OpenAIRE |
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