Hemifacial spasm: Successful treatment with felbamate
| Autor: | Gary A. Mellick |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Adult
Male Spasm medicine.medical_specialty medicine.medical_treatment Phenylcarbamates Facial Muscles Microvascular decompression Felbamate otorhinolaryngologic diseases medicine Humans Effective treatment cardiovascular diseases General Nursing Medical treatment business.industry medicine.disease Facial nerve nervous system diseases Surgery body regions stomatognathic diseases Facial muscles Treatment Outcome Anesthesiology and Pain Medicine Anticonvulsant medicine.anatomical_structure Propylene Glycols Anesthesia Anticonvulsants Neurology (clinical) business medicine.drug Hemifacial spasm |
| Zdroj: | Journal of Pain and Symptom Management. 10:392-395 |
| ISSN: | 0885-3924 |
| Popis: | Medical treatment of hemifacial spasm has generally been ineffectual. This report describes a 36 year-old man with a 7-year history of right hemifacial spasm who responded to felbamate (Felbatol®) at doses of 1800–2800 mg per day. During treatment, he was able to achieve complete control of all spontaneous facial muscle spasms at rest. Activated hemifacial spasms, initiated by chewing, speaking, smiling, or grimacing were reduced in frequency and intensity of contraction by 40%–50%. Spontaneous worsening of the hemifacial spasms occurred at a dose of 3600 mg/day. Control of the hemifacial spasm was regained at a lower dose. This is the first reported use of felbamate for the control of hemifacial spasm. Microvascular decompression of the facial nerve has been the only known effective treatment for this condition. Successful felbamate therapy would provide an alternative to those patients for whom surgery is not a treatment option. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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