Sicyos angulatus Prevents High-Fat Diet-Induced Obesity and Insulin Resistance in Mice
| Autor: | Ji Hyun Choi, Chul-Ho Lee, Jung-Ran Noh, Dong-Hee Choi, Won Keun Oh, Choi Jung Hyeon, Yong-Hoon Kim, Jae-Hoon Kim, Jin-Pyo An, Eun-Jung Kang |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
obesity Adipose tissue White adipose tissue Type 2 diabetes 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Insulin resistance Internal medicine Adipocyte insulin resistance medicine lipogenesis Sicyos angulatus business.industry General Medicine medicine.disease Obesity Endocrinology high-fat diet chemistry Lipogenesis 030211 gastroenterology & hepatology business Dyslipidemia Research Paper |
| Zdroj: | International Journal of Medical Sciences |
| ISSN: | 1449-1907 |
| Popis: | Obesity is a medical condition in which excess body fat has accumulated to a serious extent. It is a chronic disease that can lead to dyslipidemia, insulin resistance, and type 2 diabetes. In the present study, we investigated the anti-obesity effects of Sicyos angulatus (SA) extract on a high-fat diet (HFD)-induced C57BL/6J obese mice. The mice were divided into vehicle and three SA groups (25, 50, and 100 mg/kg body weight). The mice were fed a HFD with or without SA for 12 weeks. The oral administration of SA reduced body and adipose tissue weight in HFD-fed mice compared to those in the vehicle group (p |
| Databáze: | OpenAIRE |
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