High cytokine levels and cytokine storm in the novel coronavirus infection

Autor: Albina Ayratovna Zvegintseva, Albina Zainutdinovna Nigmedzyanova, Lyudmila Yurievna Kulagina, Elvina Ramisovna Kadyseva, Maksim Leonidovich Maksimov
Rok vydání: 2021
Předmět:
Zdroj: Glavvrač (Chief Medical Officer). :47-57
Popis: A review article is based on current foreign sources. The level of cytokines in the peripheral blood can be increased in many diseases, but in some cases there may be an excess of their normal concentration in tens, hundreds or more times with the development of a peculiar clinical picture, which is based on a systemic inflammatory reaction. In the literature this condition has received the figurative name «cytokine storm», which highlights an extremely violent reaction of the immune system with an unknown (often unfavorable) outcome. Close attention of the scientific world and the public to the problem of extremely high levels of cytokines in the peripheral blood (hypercytokinemia) was drawn due to the high frequency of the cytokine storm in the novel coronavirus infection.
Databáze: OpenAIRE