Neurogenesis and brain aging
| Autor: | Elena V. Stelmashook, Nickolay K. Isaev, Elisaveta E. Genrikhs |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty Aging Neurology Neurogenesis Disease Biology 03 medical and health sciences 0302 clinical medicine Alzheimer Disease medicine Animals Humans Organism Werner syndrome Progeria integumentary system General Neuroscience nutritional and metabolic diseases Brain medicine.disease Accelerated aging 030104 developmental biology Stem cell Neuroscience 030217 neurology & neurosurgery |
| Zdroj: | Reviews in the neurosciencesReferences. 30(6) |
| ISSN: | 2191-0200 |
| Popis: | Human aging affects the entire organism, but aging of the brain must undoubtedly be different from that of all other organs, as neurons are highly differentiated postmitotic cells, for the majority of which the lifespan in the postnatal period is equal to the lifespan of the entire organism. In this work, we examine the distinctive features of brain aging and neurogenesis during normal aging, pathological aging (Alzheimer’s disease), and accelerated aging (Hutchinson-Gilford progeria syndrome and Werner syndrome). |
| Databáze: | OpenAIRE |
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