An Immunohistochemical Study of Osteoprotegerin in the Human Dental Pulp
| Autor: | Katherine A. Kuntz, Cecil E. Brown, Abdel H. Kafrawy, Joseph J. Legan |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
musculoskeletal diseases
Pathology medicine.medical_specialty Endothelium H&E stain Receptors Cytoplasmic and Nuclear Inflammation Dental Caries Receptors Tumor Necrosis Factor Immunoenzyme Techniques stomatognathic system Osteoprotegerin Humans Medicine Lymphocytes Coloring Agents Hematoxylin Receptor General Dentistry Dental Pulp Fluorescent Dyes Glycoproteins Chi-Square Distribution Odontoblasts biology business.industry Macrophages Pulpitis Fibroblasts Immunohistochemistry stomatognathic diseases medicine.anatomical_structure biology.protein Eosine Yellowish-(YS) Pulp (tooth) Endothelium Vascular medicine.symptom business Peroxidase |
| Zdroj: | Journal of Endodontics. 27:666-669 |
| ISSN: | 0099-2399 |
| Popis: | This study investigated the expression of osteoprotegerin (OPG) in healthy and inflamed dental pulps. Histological sections 7 microm thick of 47 teeth, either caries-free or affected by gross caries, were used. Sections were stained with hematoxylin-eosin, and other sections of the same specimen were subjected to the avidin-biotin peroxidase complex immunohistochemical procedure for detection of OPG. The study focused on the coronal pulp that was divided into peripheral and central regions. In the peripheral pulp healthy and inflamed specimens showed high OPG immunoreactivity of the odontoblastic layer. When no inflammation was present in the central pulp OPG immunoreactivity was light. Fibroblasts and endothelial cells showed immunoreactivity ranging from none to intense. When inflammation was present in the central pulp the chronic inflammatory cells showed intense immunoreactivity. |
| Databáze: | OpenAIRE |
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