The burden of serious human fungal infections in Brazil
| Autor: | Arnaldo Lopes Colombo, J Giacomazzi, Maria Adelaide Millington, Alessandro C. Pasqualotto, Lilian C. Carneiro, David W. Denning, Ludmila Fiorenzano Baethgen |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male 0301 basic medicine medicine.medical_specialty Tuberculosis Adolescent Respiratory Tract Diseases 030106 microbiology HIV Infections Dermatology Aspergillosis Pneumocystis pneumonia Histoplasmosis Young Adult 03 medical and health sciences Cost of Illness Epidemiology medicine Humans Child Intensive care medicine Paracoccidioidomycosis business.industry Incidence Incidence (epidemiology) General Medicine Middle Aged medicine.disease Infectious Diseases Mycoses Informatics Female business Brazil |
| Zdroj: | Mycoses. 59:145-150 |
| ISSN: | 0933-7407 |
| Popis: | In Brazil, human fungal infections are prevalent, however, these conditions are not officially reportable diseases. To estimate the burden of serious fungal diseases in 1 year in Brazil, based on available data and published literature. Historical official data from fungal diseases were collected from Brazilian Unified Health System Informatics Department (DATASUS). For fungal diseases for which no official data were available, assumptions of frequencies were made by estimating based on published literature. The incidence (/1000) of hospital admissions for coccidioidomycosis was 7.12; for histoplasmosis, 2.19; and for paracoccidioidomycosis, 7.99. The estimated number of cryptococcal meningoencephalitis cases was 6832. Also, there were 4115 cases of Pneumocystis pneumonia in AIDS patients per year, 1 010 465 aspergillosis and 2 981 416 cases of serious Candida infections, including invasive and non-invasive diseases. In this study, we demonstrate that more than 3.8 million individuals in Brazil may be suffering from serious fungal infections, mostly patients with malignant cancers, transplant recipients, asthma, previous tuberculosis, HIV infection and those living in endemic areas for truly pathogenic fungi. The scientific community and the governmental agencies should work in close collaboration in order to reduce the burden of such complex, difficult-to-diagnose and hard to treat diseases. |
| Databáze: | OpenAIRE |
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