Comparison of colonic transit time between patients with constipation-predominant irritable bowel syndrome and functional constipation
| Autor: | Sahand Sohrabi, Shahin Merat, H Vahedi, Morteza Khatibian, Omid Ghanaie, Reza Ansari, Hiva Amjadi |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Constipation Colon Functional bowel disease Transit time Bowel motility Gastroenterology Cohort Studies Irritable Bowel Syndrome Young Adult Internal medicine Medicine Humans Gastrointestinal Transit business.industry Hepatology Middle Aged medicine.disease Chronic disease Chronic Disease Functional constipation Female medicine.symptom business Constipation predominant irritable bowel syndrome |
| Zdroj: | Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology. 29(2) |
| ISSN: | 0975-0711 |
| Popis: | Functional constipation (FC) and constipation-predominant IBS (C-IBS) are two main subtypes of constipation. Using radio-opaque markers is an easy and cost effective method to measure colonic transit time (CTT). We designed this study to compare the CTT between these two groups of constipated patients.Patients with chronic constipation of no organic etiology were classified as having FC or C-IBS according to the Rome II criteria. All patients ingested 10 radio opaque markers daily for six days. A plain abdominal X-ray was taken on the seventh day. To calculate the total and segmental colonic transit time in hours, number of markers in right and left colonic and rectosigmoid area were counted and multiplied by 2.4. The mean total and segmental colonic transit time were compared between the two groups.A total of 100 patients (50 FC and 50 C-IBS) were enrolled. The mean (SD) total CTT was not significantly different between FC patients (52.2 [35.5] h) and C-IBS patients (41.2 [31.6] h; p = 0.10). The mean rectosigmoid transit time was significantly slower in FC patients (19.9 [15.5] h) compared to C-IBS patients (11.9 [10.6] h; p = 0.003).Rectosigmoid transit time in FC patients is slower than in C-IBS patients. |
| Databáze: | OpenAIRE |
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